Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.


SABCS 2023 | San Antonio, TX

Dec 5 - 9, 2023

Poster
VERITAC-3: A Randomized Phase 3 Study, With a Lead in, of First Line Vepdegestrant + Palbociclib vs Letrozole + Palbociclib in Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative Advanced Breast Cancer

SA Wander et al.

SABCS 2023 | San Antonio, TX

Dec 5 - 9, 2023

Poster
Leveraging a Pharmacokinetic /Pharmacodynamic (PK/PD) Model to Guide Dose Optimization of Palbociclib in Combination With Vepdegestrant

B Jermain et al.

ESMO-ASIA 2023 | Singapore

Dec 1 - 3, 2023

Poster
Safety and Pharmacokinetics (PK) of Vepdegestrant in Japanese Patients With Estrogen Receptor (ER)+/Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Breast Cancer: Results From a Japanese Phase 1 Study

H Iwata et al.

ESMO-ASIA 2023 | Singapore

Dec 1 - 3, 2023

Poster
Global Phase 3 Studies Evaluating Vepdegestrant in Estrogen Receptor (ER)+/Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Breast Cancer: VERITAC-2 and VERITAC-3

H Iwata et al.

ESMO 2023 | Madrid, Spain

Oct 20 - 24, 2023

Poster
Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2-Advanced Breast Cancer: Update of Dose Escalation Results From a Phase 1/2 Trial

EP Hamilton et al.

ESMO 2023 | Madrid, Spain

Oct 20 - 24, 2023

Poster
Phase 1/2 Study of Bavdegalutamide, a PROteolysis TArgeting Chimera (PROTAC) Androgen Receptor Degrader, in Metastatic Castration-Resistant Prostate Cancer: Radiographic Progression-Free Survival in Patients With Androgen Receptor Ligand-Binding Domain Mutation

DP Petrylak et al.

ISSX 2023 | Boston, MA

Sep 10 - 13, 2023

Presentation
In Vitro Evaluation of PROTAC® Androgen Receptor Degrader ARV-766 for Cytochrome P450- and Transporter-Mediated Drug-Drug Interaction

JG Zhang et al.

ACCP 2023 | Bellevue, WA

Sep 10 - 12, 2023

Poster
Drug-Drug Interaction Study of the PROteolysis TArgeting Chimera (PROTAC) Androgen Receptor Degrader Bavdegalutamide in Combination With the CYP3A4 Inhibitor Itraconazole in Healthy Volunteers

J Alicea et al.

ACCP 2023 | Bellevue, WA

Sep 10 - 12, 2023

Poster
The Effect of Food and the Proton Pump Inhibitor Esomeprazole on the Single-Dose Pharmacokinetics and Safety of the PROteolysis Targeting Chimera (PROTAC) Androgen Receptor Degrader Bavdegalutamide in Healthy Volunteers

J Alicea et al.