Our Science
OUR SCIENCE
Congress Presentations
This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.
ESMO-BC 2023 | Berlin, Germany
May 11 - 13, 2023
Poster
VERITAC Update: Phase 2 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast CancerESMO-BC 2023 | Berlin, Germany
May 11 - 13, 2023
Poster
TACTIVE-E: Phase 1b Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, in Combination with Everolimus in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast CancerESMO-BC 2023 | Berlin, Germany
May 11 - 13, 2023
Poster
VERITAC-2: A Global, Randomized Phase 3 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, vs Fulvestrant in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast CancerCSHL Ubiquitins, Autophagy & Disease 2023 | Cold Spring Harbor, NY
Apr 25 - 29, 2023
Presentation
Small Molecule PROTAC® Hijacking and Structural Characterization of an E3 Ligase, KLHDC2, for Targeted Protein DegradationAACR 2023 | Orlando, FL
Apr 14 - 19, 2023
Presentation
Discovery of ARV-766, an Androgen Receptor Degrading PROTAC® for the Treatment of Men with Metastatic Castration Resistant Prostate CancerAACR 2023 | Orlando, FL
Apr 14 - 19, 2023
Poster
Mechanisms of Acquired Resistance to ARV-471, a Novel PROTAC® Estrogen Receptor DegraderAACR 2023 | Orlando, FL
Apr 14 - 19, 2023
Poster
Enhanced Efficacy of ARV-471, a Novel PROTAC® Estrogen Receptor Degrader, in Combination with Targeted Agents in Estrogen Receptor-Positive (ER+) Breast Cancer ModelsACS Spring 2023 | Indianapolis, IN
Mar 26 - 30, 2023
Presentation
The Arvinas PROTAC® Discovery Engine: PROTAC® Biophysical Characterization Fuels The Discovery Of Target And E3 Ligase Ligands For Optimized PROTAC® Degrader MoleculesAACR Special Conference: Targeting RAS 2023 | Philadelphia, PA
Mar 5 - 8, 2023