Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.

ASCO 2024 | Chicago, IL

May 31 - Jun 4, 2024

Poster
TACTIVE-K: Phase 1b/2 Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, in Combination With PF-07220060, a Cyclin-Dependent Kinase 4 Inhibitor, in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2- Advanced Breast Cancer

ML Telli et al.

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ESMO-BC 2024 | Berlin, Germany

May 15 - 17, 2024

Poster
Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, Plus Palbociclib in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2- Advanced Breast Cancer: Updated Phase 1b Cohort Results

EP Hamilton et al.

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ESMO-BC 2024 | Berlin, Germany

May 15 - 17, 2024

Poster
TACTIVE-K: Phase 1b/2 Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, in Combination With PF-07220060, a Cyclin-Dependent Kinase 4 Inhibitor, in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2- Advanced Breast Cancer

ML Telli et al.

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VIEW SUMMARY

AUA 2024 | San Antonio, TX

May 3 - 6, 2024

Poster
ARV-766, a PROTAC Androgen Receptor Degrader, Combined With Abiraterone in Novel Hormonal Agent–Naïve Metastatic Prostate Cancer: Phase 1 Cohort (Part C) of a Phase 1/2 Study

N Shore et al.

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AACR 2024 | San Diego, CA

Apr 5 - 10, 2024

Presentation
The Discovery of ARV-393, a Potent, Orally Bioavailable BCL6-Targeting PROTAC® for the Treatment of NHL

D Sherman et al.

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ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
The Effect of Itraconazole on the Pharmacokinetics of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader in Healthy Adult Participants

L Tran et al.

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ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
The Effect of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, on Dabigatran Pharmacokinetics in Healthy Adult Participants

DZ Yang et al.

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ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
Evaluation of the Effect of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, on Rosuvastatin Pharmacokinetics in Healthy Adult Participants

L Zhou et al.

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ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
Drug-Drug Interaction Study of the PROteolysis TArgeting Chimera (PROTAC) Androgen Receptor Degrader Bavdegalutamide in Combination With the P-glycoprotein Substrate Fexofenadine in Healthy Male Volunteers

J Alicea et al.

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