Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.


AACR-iCML 2024 | Philadelphia, PA

Jun 19 - 22, 2024

Poster
Trial in Progress: Phase 1 Study of ARV-393, a PROteolysis TArgeting Chimera (PROTAC) B-Cell Lymphoma 6 Degrader, in Advanced Non-Hodgkin Lymphoma

PF Caimi et al.

Biennial International LRRK2 Meeting 2024 | Crete, Greece

Jun 18 - 21, 2024

Presentation
Development of Potent, Orally Bioavailable PROTAC® LRRK2 Degrader Molecules as Potential Disease Modifying Therapeutics for Neurodegeneration

K Kelly

EHA 2024 | Madrid, Spain

Jun 13 - 16, 2024

Poster
Oral ARV-393 is a BCL6 Degrading PROTAC® Efficacious as a Monotherapy in B-Cell Lymphoma Preclinical CDX and PDX Models

SM Gough et al.

ASCO 2024 | Chicago, IL

May 31 - Jun 4, 2024

Presentation
ARV-766, A PROteolysis TArgeting Chimera (PROTAC) Androgen Receptor Degrader, in Metastatic Castration-Resistant Prostate Cancer: Initial Results of a Phase 1/2 Study

DP Petrylak et al.

ASCO 2024 | Chicago, IL

May 31 - Jun 4, 2024

Poster
TACTIVE-K: Phase 1b/2 Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, in Combination With PF-07220060, a Cyclin-Dependent Kinase 4 Inhibitor, in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2- Advanced Breast Cancer

ML Telli et al.

ESMO-BC 2024 | Berlin, Germany

May 15 - 17, 2024

Poster
Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, Plus Palbociclib in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2- Advanced Breast Cancer: Updated Phase 1b Cohort Results

EP Hamilton et al.

ESMO-BC 2024 | Berlin, Germany

May 15 - 17, 2024

Poster
TACTIVE-K: Phase 1b/2 Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, in Combination With PF-07220060, a Cyclin-Dependent Kinase 4 Inhibitor, in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2- Advanced Breast Cancer

ML Telli et al.

AUA 2024 | San Antonio, TX

May 3 - 6, 2024

Poster
ARV-766, a PROTAC Androgen Receptor Degrader, Combined With Abiraterone in Novel Hormonal Agent–Naïve Metastatic Prostate Cancer: Phase 1 Cohort (Part C) of a Phase 1/2 Study

N Shore et al.

AACR 2024 | San Diego, CA

Apr 5 - 10, 2024

Presentation
The Discovery of ARV-393, a Potent, Orally Bioavailable BCL6-Targeting PROTAC® for the Treatment of NHL

D Sherman et al.

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