Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.


ESMO 2025 | Berlin, Germany

Oct 17 - 21, 2025

Presentation
TACTIVE-N: Phase 2 Study of Neoadjuvant Vepdegestrant, a PROTAC Estrogen Receptor (ER) Degrader, or Anastrozole in Postmenopausal ER+/Human Epidermal Growth Factor Receptor 2-Negative Localized Breast Cancer

PA Fasching et al.

ESMO 2025 | Berlin, Germany

Oct 17 - 21, 2025

Presentation
Patient-Reported Outcomes (PROs) with Vepdegestrant (VEP) vs Fulvestrant (FUL) in Patients (pts) with Estrogen Receptor (ER) 1 Gene Mutated (ESR1m) ER+/Human Epidermal Growth Factor Receptor 2 (HER2): Advanced Breast Cancer (aBC) in the Phase 3 VERITAC-2 Trial

M Campone et al.

WMS 2025 | Vienna, Austria

Oct 7 - 11, 2025

Poster
Oral ARV-027 Induces PolyQ-AR Degradation and Improves Muscle Strength and Endurance in a Murine Model of SBMA

J Gregory et al.

MDS 2025 | Honolulu, HI

Oct 5 - 9, 2025

Poster
First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of ARV-102, a PROTAC LRRK2 Degrader, in Healthy Participants

L Smits et al.

MDS 2025 | Honolulu, HI

Oct 5 - 9, 2025

Poster
First Clinical Trials of ARV-102, a PROTAC LRRK2 Degrader: Characterization of Pathway Engagement in Healthy Volunteers and Patients With Parkinson’s Disease

L Smits et al.

ISSX 2025 | Chicago, IL

Sep 21 - 24, 2025

Poster
Absorption, Metabolism, Excretion, and Pharmacokinetics of [14C] Vepdegestrant in Healthy Adult Participants

TR Johnson et al.

ACCP 2025 | Phoenix, AZ

Sep 14 - 16, 2025

Poster
A Relative Bioavailability Study of Vepdegestrant Tablets in Healthy Adult Participants

DZ Yang et al.

SOHO 2025 | Houston, TX

Sep 3 - 6, 2025

Poster
Phase 1 Study of ARV-393, a PROTAC BCL6 Degrader, in Advanced Non-Hodgkin Lymphoma

PF Caimi et al.

SOHO 2025 | Houston, TX

Sep 3 - 6, 2025

Poster
ARV-393, a PROTAC BCL6 Degrader, Combined With Biologics or Small-Molecule Inhibitors Induces Tumor Regressions in Diffuse Large B-Cell Lymphoma Models

A Van Acker et al.