Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.


ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
The Effect of Itraconazole on the Pharmacokinetics of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader in Healthy Adult Participants

L Tran et al.

ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
The Effect of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, on Dabigatran Pharmacokinetics in Healthy Adult Participants

DZ Yang et al.

ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
Evaluation of the Effect of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, on Rosuvastatin Pharmacokinetics in Healthy Adult Participants

L Zhou et al.

ASCPT 2024 | Colorado Springs, CO

Mar 27 - 29, 2024

Poster
Drug-Drug Interaction Study of the PROteolysis TArgeting Chimera (PROTAC) Androgen Receptor Degrader Bavdegalutamide in Combination With the P-glycoprotein Substrate Fexofenadine in Healthy Male Volunteers

J Alicea et al.

ASCO-GU 2024 | San Francisco, CA

Jan 25 - 27, 2024

Poster
Real-World Outcomes of Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Tumors Harboring Androgen Receptor (AR) Ligand-Binding Domain (LBD) Mutations

TF Stewart et al.

SABCS 2023 | San Antonio, TX

Dec 5 - 9, 2023

Presentation
Vepdegestrant, a PROteolysis Targeting Chimera (PROTAC) Estrogen Receptor Degrader, Plus Palbociclib in Estrogen Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Phase 1b Cohort

EP Hamilton et al.

SABCS 2023 | San Antonio, TX

Dec 5 - 9, 2023

Poster
Updated Results From VERITAC Evaluating Vepdegestrant, a PROteolysis Targeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, in ER–Positive/Human Epidermal Growth Factor Receptor 2 (HER2)–Negative Advanced Breast Cancer

SA Hurvitz et al.

SABCS 2023 | San Antonio, TX

Dec 5 - 9, 2023

Poster
TACTIVE-U: Phase 1b/2 Umbrella Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, Combined With Other Anticancer Treatments in ER-Positive Advanced or Metastatic Breast Cancer

C Isaacs et al.

SABCS 2023 | San Antonio, TX

Dec 5 - 9, 2023

Poster
VERITAC-2: A Phase 3 Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, vs Fulvestrant in ER Positive/Human Epidermal Growth Factor Receptor 2 (HER2) Negative Advanced Breast Cancer

M Campone et al.