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  • Our Science
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05DecDecember 5, 2023

VERITAC-2: A Phase 3 Study of Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, vs Fulvestrant in ER Positive/Human Epidermal Growth Factor Receptor 2 (HER2) Negative Advanced Breast Cancer

05DecDecember 5, 2023

VERITAC-3: A Randomized Phase 3 Study, With a Lead in, of First Line Vepdegestrant + Palbociclib vs Letrozole + Palbociclib in Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative Advanced Breast Cancer

05DecDecember 5, 2023

Leveraging a Pharmacokinetic /Pharmacodynamic (PK/PD) Model to Guide Dose Optimization of Palbociclib in Combination With Vepdegestrant

01DecDecember 1, 2023

Safety and Pharmacokinetics (PK) of Vepdegestrant in Japanese Patients With Estrogen Receptor (ER)+/Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Breast Cancer: Results From a Japanese Phase 1 Study

01DecDecember 1, 2023

Global Phase 3 Studies Evaluating Vepdegestrant in Estrogen Receptor (ER)+/Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Breast Cancer: VERITAC-2 and VERITAC-3

20OctOctober 20, 2023

Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor Degrader, in Estrogen Receptor+/Human Epidermal Growth Factor Receptor 2-Advanced Breast Cancer: Update of Dose Escalation Results From a Phase 1/2 Trial

20OctOctober 20, 2023

Phase 1/2 Study of Bavdegalutamide, a PROteolysis TArgeting Chimera (PROTAC) Androgen Receptor Degrader, in Metastatic Castration-Resistant Prostate Cancer: Radiographic Progression-Free Survival in Patients With Androgen Receptor Ligand-Binding Domain Mutation

02JunJune 2, 2023

TACTIVE-U: Phase 1b/2 Umbrella Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, Combined with Other Anticancer Treatments in ER+ Advanced or Metastatic Breast Cancer

02JunJune 2, 2023

VERITAC-2: A Global, Randomized Phase 3 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, vs Fulvestrant in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast Cancer

11MayMay 11, 2023

TACTIVE-N: Open-Label, Randomized, Noncomparative Neoadjuvant Phase 2 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, or Anastrozole in Postmenopausal Women with ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Localized Breast Cancer

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