Our Science

OUR SCIENCE

Congress Presentations

This section includes posters and presentations related to Arvinas’ PROTAC science, discovery compounds, and clinical-stage assets presented at scientific congresses in the past three years.


CSHL Ubiquitins, Autophagy & Disease 2023 | Cold Spring Harbor, NY

Apr 25 - 29, 2023

Presentation
Small Molecule PROTAC® Hijacking and Structural Characterization of an E3 Ligase, KLHDC2, for Targeted Protein Degradation

K Digianantonio

AACR 2023 | Orlando, FL

Apr 14 - 19, 2023

Presentation
Discovery of ARV-766, an Androgen Receptor Degrading PROTAC® for the Treatment of Men with Metastatic Castration Resistant Prostate Cancer

LB Snyder et al.

AACR 2023 | Orlando, FL

Apr 14 - 19, 2023

Poster
Mechanisms of Acquired Resistance to ARV-471, a Novel PROTAC® Estrogen Receptor Degrader

J Teh et al.

AACR 2023 | Orlando, FL

Apr 14 - 19, 2023

Poster
Enhanced Efficacy of ARV-471, a Novel PROTAC® Estrogen Receptor Degrader, in Combination with Targeted Agents in Estrogen Receptor-Positive (ER+) Breast Cancer Models

J Teh et al.

ACS Spring 2023 | Indianapolis, IN

Mar 26 - 30, 2023

Presentation
The Arvinas PROTAC® Discovery Engine: PROTAC® Biophysical Characterization Fuels The Discovery Of Target And E3 Ligase Ligands For Optimized PROTAC® Degrader Molecules

A Harbin

AACR Special Conference: Targeting RAS 2023 | Philadelphia, PA

Mar 5 - 8, 2023

Presentation
KRAS-Targeted PROTAC® Degraders Are Broadly Efficacious Against KRAS Dependent Tumor Models

K Smith

ASCO-GU 2023 | San Francisco, CA

Feb 16 - 18, 2023

Poster
A Phase 2 Expansion Study of ARV-766, a PROTAC Androgen Receptor (AR) Degrader, in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

DP Petrylak et al.

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