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  • Our Science
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27AugAugust 27, 2023

Development of Potent, Orally Bioavailable, and Highly Selective LRRK2 PROTAC® Degrader Molecules as Potential Disease Modifying Therapeutics for Parkinson’s Disease

27AugAugust 27, 2023

LRRK2 PROTAC® Degrader Molecules Induce Robust Biomarker Responses in Preclinical In Vivo Pharmacology Studies Following Acute and Chronic Oral Dosing

06JunJune 6, 2023

ASCO 2023

02JunJune 2, 2023

TACTIVE-U: Phase 1b/2 Umbrella Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, Combined with Other Anticancer Treatments in ER+ Advanced or Metastatic Breast Cancer

02JunJune 2, 2023

VERITAC-2: A Global, Randomized Phase 3 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, vs Fulvestrant in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast Cancer

26MayMay 26, 2023

ACS Spring 2023

13MayMay 13, 2023

ESMO-BC 2023

11MayMay 11, 2023

TACTIVE-N: Open-Label, Randomized, Noncomparative Neoadjuvant Phase 2 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, or Anastrozole in Postmenopausal Women with ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Localized Breast Cancer

11MayMay 11, 2023

VERITAC Update: Phase 2 Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast Cancer

11MayMay 11, 2023

TACTIVE-E: Phase 1b Study of ARV-471, a PROteolysis TArgeting Chimera (PROTAC) Estrogen Receptor (ER) Degrader, in Combination with Everolimus in ER+/Human Epidermal Growth Factor Receptor 2 (HER2)-Advanced Breast Cancer

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