A Decade of Arvinas
Forging New Scientific Frontiers in Drug Discovery
2023 marked a monumental milestone in Arvinas’ history as we celebrated our 10-year anniversary.
Over the past decade, Arvinas has made incredible strides in pioneering targeted protein degradation research.
From creating the first oral PROTAC® protein degraders for clinical trials, to the initiation of Phase 3 clinical studies, we’ve remained committed to pushing the boundaries of what’s possible in biotech.
1O Years of Scientific Discovery
Arvinas is founded by Yale professor Craig Crews with the goal of turning PROTAC® protein degraders into patient therapies
Arvinas creates the first oral PROTAC® protein degraders for clinical trial evaluation
Arvinas creates the first blood-brain barrier-crossing PROTAC® protein degraders
Two Arvinas PROTAC® degraders, bavdegalutamide and vepdegestrant, enter clinical studies
Proof of concept is achieved for bavdegalutamide and vepdegestrant
Arvinas partners with Pfizer to co-develop and co-commercialize vepdegestrant
Arvinas initiates first registrational study with vepdegestrant
Bavdegalutamide and vepdegestrant are currently under investigation. Their safety and effectiveness have not yet been established.
1O Years of Scientific Discovery
1O Years of Scientific Discovery
Arvinas initiates first registrational study with vepdegestrant
Arvinas PROTAC® degraders, bavdegalutamide and vepdegestrant, enter clinical studies
Efficacy proof of concept is achieved for bavdegalutamide and vepdegestrant
Arvinas partners with Pfizer to co-develop and co-commercialize vepdegestrant
Arvinas’ founder, Craig Crews, publishes the first paper describing heterobifunctional protein degraders
Arvinas is founded with the goal to turn protein degraders into patient therapies
Arvinas creates the first oral PROTAC® protein degrader
Arvinas creates the first blood-brain barrier-crossing PROTAC® protein degrader
Bavdegalutamide and vepdegestrant are currently under investigation.
Their safety and effectiveness have not yet been established.
Team Arvinas: Stories of Discovery and Impact
We are incredibly proud of the milestones we have achieved thus far. But don’t just take our word for it— hear firsthand from Arvinas colleagues as they reflect on our remarkable journey.
What’s Next: Looking Towards the Future
We couldn’t be more excited about the future of our company! Take a closer look at those shaping the future of Arvinas and driving us toward even greater success.
If you’re inspired, please take a look at the current list of opportunities to join our team.