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Open Positions: HEOR Director, Medical Affairs

Arvinas is a clinical-stage biopharmaceutical company leading the way in targeted protein degradation therapeutics. Arvinas is the first company to focus solely on protein degradation and its platform technology is the most advanced in the field. Since its founding in 2013, Arvinas’ PROTAC® Discovery Engine has been driving the most significant breakthroughs in the industry. Arvinas’ pipeline encompasses a range of validated and undruggable targets in oncology, immuno-oncology, and neuroscience. This includes three clinical-stage programs: bavdegalutamide (ARV-110) and ARV-766, which are being developed as potential treatments for men with late-line metastatic castrate-resistant prostate cancer, and ARV-471, which is being developed as a potential treatment for patients with breast cancer.

#TeamArvinas is made up of more than 350 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and purpose – to improve the well-being of patients and families impacted by the devastating diseases Arvinas is working to treat. It’s an exciting time to be in drug development and it’s an exciting time to be at Arvinas. But don’t just take our word for it – here’s what Arvinas employees are saying. For more information, please visit

Position Summary

The HEOR Director will be responsible for leading the design and implementation of health economics and outcomes research strategy to support Arvinas’ oncology portfolio. The HEOR Director will collaborate with cross-functional teams to drive HEOR strategy and implement HEOR and RWD activities to support products from clinical development through post-launch and life-cycle.

This position reports to the Head of Medical Affairs, and will be located at our headquarters in New Haven, CT or may be performed remotely from a location within the U.S.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

  • Lead the development and execution of the evidence generation strategy to support product clinical and economic value, in collaboration with cross-functional partners
  • Responsible for the design, conduct, and management of HEOR and RWD studies, such as early economic models, burden of illness studies, external control arms to support single arm trials, etc.
  • Manage vendors in the conduct of HEOR and RWE projects
  • Provide input into Patient Reported Outcomes (PRO) endpoints for clinical trials
  • Generate publications to communicate study findings
  • Support of regulatory submissions and HTA launch readiness and submissions, including development of comprehensive global tools such as dossiers and economic models to support pricing and market access
  • Serve as core member of cross-functional development and medical teams


  • 10+ years of related experience (e.g., academia, consulting, and/or industry) with a minimum of 4 years in pharmaceutical or biotech industry,
  • Oncology experience required
  • History of peer-reviewed publications
  • Strong understanding of drug development process and life-cycle management
  • Strong knowledge of major markets and their HTA policies
  • Excellent understanding of HEOR and RWE concepts with hands on experience with HEOR methodologies across all phases of the product life cycle
  • Previous experience in economic modeling, econometrics, retrospective database analysis, and/or epidemiology is preferred
  • Able to prioritize and manage several projects simultaneously.
  • Ability to work in a fast-paced and ever-changing environment
  • Ability to travel up to 20% of time


  • Advanced degree (Masters. PhD, PharmD) in relevant field (e.g., outcomes research, health services research, epidemiology, health economics, health policy or related fields)


Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit

Arvinas is an Equal Opportunity employer

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