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Open Positions: Director, Bioanalysis

Arvinas is a clinical-stage biopharmaceutical company leading the way in targeted protein degradation therapeutics. Arvinas is the first company to focus solely on protein degradation and its platform technology is the most advanced in the field. Since its founding in 2013, Arvinas’ PROTAC® Discovery Engine has been driving the most significant breakthroughs in the industry. Arvinas’ pipeline encompasses a range of validated and undruggable targets in oncology, immuno-oncology, and neuroscience. This includes three clinical-stage programs: bavdegalutamide (ARV-110) and ARV-766, which are being developed as potential treatments for men with late-line metastatic castrate-resistant prostate cancer, and ARV-471, which is being developed as a potential treatment for patients with breast cancer.

#TeamArvinas is made up of more than 350 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and purpose – to improve the well-being of patients and families impacted by the devastating diseases Arvinas is working to treat. It’s an exciting time to be in drug development and it’s an exciting time to be at Arvinas. But don’t just take our word for it – here’s what Arvinas employees are saying. For more information, please visit www.arvinas.com.

Position Summary

We have an exciting opening for a seasoned bioanalytical scientist with expertise in the area of small molecule bioanalysis. The incumbent will contribute as a bioanalytical expert supporting drug discovery through all stages of drug development, with a focus on regulated bioanalysis for nonclinical GLP programs and clinical programs.

This position reports to the Head, Nonclinical Sciences and is located in New Haven, CT or can be performed remotely from within the United States.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

  • Contribute to the formulation and execution of bioanalytical strategy supporting all facets of Arvinas bioanalytical needs from a portfolio, project, or functional levels.
  • Participate in the non-regulated bioanalytical support for in vitro ADME, preclinical in vivo PK, ADME, and PK/PD studies, DRF toxicology studies and regulated and GLP-compliant bioanalytical work for GLP toxicology and clinical pharmacology.
  • Contribute to bioanalysis outsource strategy; evaluate, recommend, or select bioanalytical CROs to ensure timely and stage-appropriate bioanalytical support of Arvinas projects.
  • Serve as Arvinas SME and oversee the development, qualification, or validation of bioanalytical methods for various matrices and species
  • Serve as Arvinas representative to coordinate all facets of bioanalysis and ensure timely delivery of high-quality bioanalytical results to support project progression and decision-making
  • Ensure high quality and regulatory compliance for all Arvinas regulated bioanalytical work
  • Stay up to date with the scientific advance and evolving domestic (FDA) and international (ICH, etc) regulatory landscape for bioanalysis for the pharmaceutical industry.

Qualifications

  • 10+ years of direct experience in bioanalysis in the biopharmaceutical industry or CROs supporting pharmaceutical development, with a focus on small molecules
  • Expertise on LC/MS/MS based bioanalytical science including theoretical background and practical problem-solving skills
  • In-depth knowledge of current regulatory requirements and up -to-date knowledge of evolving regulatory landscape for GLP bioanalysis
  • General knowledge of drug discovery and development process.
  • Experience in bioanalytical outsourcing

Education

  • Ph.D. in chemistry, pharmaceutical science, or related scientific discipline

#LI-Remote

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer

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